For a 12-year-old girl with cystic fibrosis, what therapy should be initiated upon her admission?

In the context of a 12-year-old girl with cystic fibrosis being admitted, the most appropriate initial therapy involves administering nebulized saline. This treatment is beneficial for patients with cystic fibrosis as it helps to hydrate and thin the mucus in the lungs, making it easier to clear. Nebulized saline can also help alleviate some of the respiratory distress that individuals with cystic fibrosis often experience.

Furthermore, while supplemental oxygen may be utilized in cases where the patient is hypoxemic, it is not the first-line treatment upon admission. The emphasis on nebulized saline stems from its direct effect on pulmonary function, which is crucial given the patient's underlying condition. Starting intravenous antibiotics is more relevant if there is a diagnosed infection, which may be assessed later based on clinical findings and cultures. Measuring peak flow rates can provide useful information concerning respiratory status, but it is not typically prioritized as immediate therapy in the context of cystic fibrosis exacerbation. Thus, initiating nebulized saline aligns with the immediate therapeutic goals for managing cystic fibrosis symptoms.